48975
Fluka
Gliotoxin from Gliocladium fimbriatum
BioChemika, ≥98.0% (TLC)
| CAS Number: | 67-99-2 |
| Linear Formula: | C13H14N2O4S2 |
| Molecular Weight: | 326.39 |
| Beilstein Registry Number: | 50675 |
| MDL number: | MFCD00058534 |
Description
| Application | Noncompetitive inhibitor of the chymotrypsin-like activity of the 20S proteasome in vitro. |
| Other Notes | Antiphagocytic and immunomodulating agent which acts by blocking membrane thiol groups1,2 |
Properties
| product line | BioChemika |
| assay | ≥98.0% (TLC) |
| solubility | chloroform: 10 mg/mL, clear, colorless |
| storage temp. | 2-8°C |
Safety
| Personal Protective Equipment | Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges |
| Hazard Codes | T |
| Risk Statements | 25 |
| Safety Statements | 36/37/39-45 |
| RIDADR | UN3462 6.1/PG 3 |
| WGK Germany | 3 |
| RTECS | KB4725000 |
Related Products
| Replaced by | G9893, Gliotoxin from Gliocladium fimbriatum |
References
| Cited Reference | 1. A. Mulbacher et al. J. Gen. Microbiol. 131, 1251, (1985) Abstract |
| 2. R.J. Jones, J.G. Hancock J. Gen. Microbiol. 134, 2067, (1988) | |
| reference | Kroll, M., The secondary fungal metabolite gliotoxin targets proteolytic activities of the proteasome. Chem. Biol. 10, 689, (1999) |
| Merck | Merck 13,4454 |
| Beilstein | Beil. 27,IV,8902 |
